Member publications
This is the Harvard NeuroDiscovery archive of scientific publications from 2007, authored by members of our community. The publications posted here were supported at least in part by the Harvard NeuroDiscovery Center. For publications from 2001 to 2006, please click on publication year to the left.
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*Published with acknowledgment of Harvard Neurodiscovery Center (formerly the Harvard Center for Neurodegeneration & Repair or "HCNR") resources.
2008
April
Teng X, Keys H, Yuan J, Degterev A, Cuny GD. "Structure-activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors." Bioorganic & Medicinal Chemistry Letters. Electronically published April 25, 2008.*
February
Miller SL, Celone K, Depeau K, Diamond E, Dickerson BC, Rentz D, Pihlajamäki M, Sperling RA. February 12, 2008. "Age-related memory impairment associated with loss of parietal deactivation but preserved hippocampal activation." Proceedings of the National Academy of Sciences, USA 105(6): 2181-6. Electronically published January 31, 2008.*
January
Wang M, Zhou X, Li F, Huckins J, King RW, Wong ST. January 1, 2008. "Novel cell segmentation and online SVM for cell cycle phase identification in automated microscopy." Bioinformatics 24(1): 94-101. Electronically published November 7, 2007.*
Wang J, Zhou X, Bradley PL, Chang SF, Perrimon N, Wong ST. January 2008. "Cellular phenotype recognition for high-content RNA interference genome-wide screening." Journal of Biomolecular Screening 13(1): 29-39.*
2007
December
Teng X, Keys H, Jeevanandam A, Porco JA Jr, Degterev A, Yuan J, Cuny GD. December 15, 2007. "Structure-activity relationship study of [1,2,3]thiadiazole necroptosis inhibitors." Bioorganic & Medicinal Chemistry Letters 17(24): 6836-40. Electronically published October 17, 2007.*
Stein RL. December 2007. "A new model for academics based drug discovery." Current Alzheimer Research 4(5): 574-6.*
Glicksman MA, Cuny GD, Liu M, Dobson B, Auerbach K, Stein RL, Kosik KS. December 2007. "New approaches to the discovery of cdk5 inhibitors." Current Alzheimer Research 4(5): 547-9.*
November
Peled S. November 2007. "New perspectives on the sources of white matter DTI signal." IEEE Transactions on Medical Imaging 26(11):1448-55.*
September
Seng S, Avraham H, Li H, Jiang S, Avraham S. September 15, 2007. "The Nuclear Matrix Protein, NRP/B, Enhances Nrf2-Mediated Oxidative Stress Responses in Breast Cancer Cells." Cancer Research 67(18): 8596-604.
Li G, Liu T, Tarokh A, Nie J, Guo L, Mara A, Holley S, Wong ST. September 4, 2007. "3D cell nuclei segmentation based on gradient flow tracking." BMC Cell Biology 8:40.*
Srinivasan R, Zhou X, Miller E, Lu J, Litchman J, Wong ST. Fall 2007. "Automated axon tracking of 3D confocal laser scanning microscopy images using guided probabilistic region merging." Neuroinformatics 5(3): 189-203.*
August
The International Multiple Sclerosis Genetics Consortium. August 30, 2007. "Risk Alleles for Multiple Sclerosis Identified by a Genomewide Study." New England Journal of Medicine. Electronically published July 29, 2007.*
Chung CY, Koprich JB, Endo S, Isacson O. August 1, 2007. "An Endogenous Serine/Threonine Protein Phosphatase Inhibitor, G-Substance, Reduces vulnerability in Models of Parkinson's Disease." Journal of Neuroscience 27(31): 8314-23.*
July
Liu B-F, Liang J. July 23, 2007. "Protein-protein interactions among human lens acidic and basic B-crystallins." FEBS Letters 581: 3936-42.*
Pack-Chung, Eunju. July 22, 2007. "A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport." Nature Neuroscience 10: 980-989.*
Alvarez VA, Ridenour DA, Sabatini BL. July 11, 2007. "Distinct Structural and Ionotropic Roles of NMDA Receptors in Controlling Spine and Synapse Stability." The Journal of Neuroscience 27(28): 7364-76.*
Mermerian AH, Case A, Stein RL, Cuny GD. July 1, 2007. "Structure-activity relationship, kinetic mechanism, and selectivity for a new class of ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitors." Bioorganic & Medicinal Chemistry Letters 17(13): 3729-32. Electronically published April 10, 2007.*
June
Liu B-F, Anbarasu K, Liang J. June 14, 2007. "Confocal fluorescence resonance energy transfer microscopy study of protein-protein interactions of lens crystallins in living cells." Molecular Vision 13: 854-61.*
Lee TH, Seng S, Sekine M, Hinton C, Fu Y, Avraham H, Avraham S. June 5, 2007. "Vascular Endothelial Growth Factor Mediates Intracrine Survival in Human Breast Carcinoma Cells through Internally Expressed VEGFR1/FLT1." PLoS Medine 4(6): e186.
April
Jiang S, Seng S, Avraham H, Kim T, and Avraham S. April 20, 2007. "Process Elongation of Oligodendrocytes is promoted by the Kelch-related Protein MRP2/KLHL1." Journal of Biological Chemistry 282(16): 12319-29.
Jagtap PG, Degterev A, Choi S, Keys H, Yuan J, Cuny GD. April 19, 2007. "Structure-Activity Relationship Study of Tricyclic Necroptosis Inhibitors." Journal of Medicinal Chemistry 50(8): 1886-95. Electonically published March 16, 2007.*
March
Certel SJ, Savella MG, Schlegel DC, Kravitz EA. March 13, 2007. "Modulation of Drosophila male behavioral choice." Proceedings of the National Academy of Sciences, USA 104(11): 4706-11.*
Khoury JE, Toft M, Hickman SE, Means TK, Terada K, Geula C, Luster AD. 2007. "Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease." Nature Medicine. Electronically published March 11, 2007.*
The International Multiple Sclerosis Genetics Consortium. March 2007. "A second major histocompatibility complex susceptibility locus for multiple sclerosis." Annals of Neurology 61(3): 228-36. Electronically published January 24, 2007.*
January
Case A, Stein RL. January 30, 2007. "Kinetic analysis of the interaction of tissue transglutaminase with a nonpeptidic slow-binding inhibitor." Biochemistry 46(4): 1106-15.*