2002 - 2001 Publications Archive
*Published with acknowledgment of Harvard Neurodiscovery Center (formerly the Harvard Center for Neurodegeneration & Repair or "HCNR") resources.
2002
December
Stowers RS, Megeath LJ, Gorska-Andrzejak J, Meinertzhagen IA, Schwarz TL. December 19, 2002. "Axonal Transport of Mitochondria to Synapses Depends on Milton, a Novel Drosophila Protein." Neuron 36(6): 1063-77.
Sandler VM, Wang S, Angelo K, Lo HG, Breakefield XO, Clapham DE. December 15, 2002. "Modified herpes simplex virus delivery of enhanced GFP into the central nervous system." Journal of Neuroscience Methods 121(2): 211-9.
Fukumoto H, Deng A, Irizarry MC, Fitzgerald ML, Rebeck GW. December 13, 2002. "Induction of the Cholesterol Transporter ABCA1 in Central Nervous System Cells by Liver X Receptor Agonists Increases Secreted A-beta Levels." Journal of Biological Chemistry 277(50): 48508-13.*
Moore KJ, El Khoury J, Medeiros LA, Terada K, Geula C, Luster AD, Freeman MW. December 6, 2002. "A CD36-initiated Signaling Cascade Mediates Inflammatory Effects of -Amyloid." Journal of Biological Chemistry 277(49): 47373-9.
Kosik KS, Ahn J, Stein R, Yeh LA. December 2002. "Discovery of Compounds that will prevent tau pathology." Journal of Molecular Neuroscience 19(3): 261-6.
Butte A. December 2002. "The use and analysis of microarray data." Nature Reviews Drug Discovery 1(12): 951-60.
November
Chung S, Sonntag K, Bjorklund L, Kim K, Isacson O. November 2002. "Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons." European Journal of Neuroscience 16(10): 1829-38.*
October
Selkoe DJ. October 25, 2002. "Alzheimer's Disease Is a Synaptic Failure." Science 298(5594): 789-91.*
Liu Y, Fallon L, Lashuel HA, Liu Z, Lansbury PT Jr. October 18, 2002. "The UCH-L1 Gene Encodes Two Opposing Enzymatic Activities that Affect Alpha-Synuclein Degradation and Parkinson's Disease Susceptibility." Cell 111(2): 209-18.*
Lashuel HA, Petre BM, Wall J, Simon M, Nowak RJ, Walz T, Lansbury PT Jr. October 4, 2002. "alpha-Synuclein, Especially the Parkinson's Disease-associated Mutants, Forms Pore-like Annular and Tubular Protofibrils." Journal of Molecular Biology 322(5): 1089-102.*
May
Kimberly WT, Xia W, Selkoe DJ, Campbell WA. May 2002. "Amyloid-lowering Isocoumarins Are Not Direct Inhibitors of y-secretase." Nature Cell Biology 4(5): E110-1.
March
Hsich G, Sena-Esteves M, Breakefield XO. March 20, 2002. "Critical issues in gene therapy for neurological disease." Human Gene Therapy 13: 579-604.
Campbell WA, Iskandar MK, Reed ML, Xia W. March 12, 2002. "Endoproteolysis of Presenilin in Vitro: Inhibition by gamma-Secretase Inhibitors." Biochemistry 41(10): 3372-9.*
February
Isacson O, Sanchez-Pernaute R, Chung S, Brownell A, Kim K, Bjorklund LM. February 19, 2002. "Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model." Proceedings of the National Academy of Sciences, USA 99(4): 2344-9.
January
Bertram L, Blacker M, Saunders AJ, Tanzi RE, Albert DS. January 1, 2002. "Results of a High-resolution Genome Screen of 437 Alzheimer's Disease Families." Human Molecular Genetics 12: 23-32.*
Xing X, Yeh L. 2002. "Utilization of a Copper-catalyzed Diaryl Ether Synthesis for the Preparation of Verbenachalcone." Tetrahedron 58: 7903-10.*
2001
October
Kimberly WT, Guenette SY, Selkoe DJ. October 26, 2001. "The Intracellular Domain of the beta-Amyloid Precursor Protein Is Stabilized by Fe65 and Translocates to the Nucleus in a Notch-like Manner." Journal of Biological Chemistry 276(43): 40288-92. Electronically published September 5, 2001.
Bertram L, Tanzi RE. October 25, 2001. "New Frontiers in Alzheimer's Disease Genetics." Neuron 32(2): 181-4.
Chou TC, Lee CE, Lu J, Elmquist JK, Hara J, Willie JT, Beuckmann CT, Chemelli RM, Sakurai T, Yanagisawa M, Saper C, Scammell TB. October 1, 2001. "Orexin (Hypocretin) Neurons Contain Dynorphin." Journal of Neuroscience 21(19): RC168: 1-6.
Bertram L, Tanzi RE. October 2001. "Dancing in the Dark?: The Status of Late-Onset Alzheimer's Disease Genetics." Journal of Molecular Neuroscience 17(2): 127-36.